μ-Fill Pigm 400 Biologique Recherche

This single-use patch mask contains tyrosinase inhibitors that protect the skin from damage caused by the sun, hormones, and free radicals. Hyaluronic acid transports these active ingredients, regulating melanin synthesis and transfer to prevent surface discoloration. Thanks to its exceptional ingredients, it penetrates the deeper layers of the epidermis and lightens localized dark spots.

It also reduces brown spots on the skin's surface, restoring an even skin tone. It limits the oxidation of proteins responsible for lipofuscin synthesis to reduce skin pigmentation. It regulates the synthesis of melanin and its transfer to keratinocytes to inhibit skin pigmentation on the surface. Its anti-glycation action reduces the level of AGEs in the cellular environment, fighting against the overproduction of melanin. It exerts an antioxidant activity, protecting cells and controlling the production of melanin induced by oxidative stress.

Apply after preparing the skin with the appropriate treatment milk and P50 lotion. Open the blister pack and remove the protective film. Apply the side of the patch containing the microneedles directly to the skin and press lightly with your fingertips to ensure it adheres completely to the pigmented area. Leave on, preferably overnight or for a minimum of 3 hours. This exposure time is necessary for the micro-needles to dissolve and release the active ingredients. After this time, discard the patch. Apply as a treatment for 3 weeks (once a week). The treatment can be extended as needed, maintaining the application schedule. Store the packaging protected from direct light and intense heat sources. For external use only. The skin will then close the micro-perforations created. During this time, the skin remains protected thanks to the patch's protective film. μ-Fill PIGM 400 is used as a shock treatment, applied 3 times per week for 1 month. After the treatment is complete, maintenance can be performed to ensure results, applying a single patch per week.

Hexylresorcinol and Niacinamide (μ-Fill) – Regulates melanin production and reduces and corrects discoloration. Evens skin tone. Niacinamide (Vitamin B3): helps even skin tone, giving it a more youthful appearance. It has a depigmenting and brightening effect. In addition, this active ingredient has anti-inflammatory properties and strengthens the skin barrier by regulating its hydrolipidic balance, making it beneficial in cases of acne and rosacea. They stimulate epidermal renewal and help eliminate melanin stored in keratinocytes. It is a precursor to a series of cofactors that participate in many enzymatic reactions in the skin, thus positively influencing numerous skin processes. Tranexamic Acid – Regulates the cellular mechanisms involved in the formation of dark spots, preventing and reducing pigment production. Besides helping to diminish dark spots, hyperpigmentation, and melasma, tranexamic acid is excellent for brightening the skin (especially when used in conjunction with vitamin C) and for reducing the appearance of acne scars. So, if you want a more even skin tone and a more radiant complexion, this acid is ideal. By decreasing melanin synthesis, tranexamic acid acts as a depigmenting agent that prevents the formation of new melanin in hyperpigmented areas. Hyaluronic Acid – It is one of the main components of our extracellular matrix (the framework in which our skin cells sit) and also plays a vital role in moisture retention. Capable of holding up to 1,000 times its molecular weight in water, hyaluronic acid penetrates the skin and binds skin cells with water, infusing all layers of the skin with valuable, rejuvenating moisture. Hyaluronic acid strengthens the skin's natural barriers to lock in moisture, thus achieving an even more dramatic hydrating effect. By improving the skin's natural barriers, the skin is better able to defend itself against environmental factors and pollutants. L-Carnosine – Saccharification, or the accumulation of sugar in cells, is one of the causes of skin aging, along with exposure to UVA and UVB rays from the sun. However, it has been largely unknown until now, when it is being demonstrated that active ingredients like L-Carnosine significantly and demonstrably reduce saccharification in cells. Carnosine works in conjunction with other biological antioxidants, such as vitamins E and C, zinc, and selenium, thus conserving their consumption in tissues. It stabilizes and protects the cell membrane, preventing oxidative stress caused by free radicals. It prevents the formation of oxidative stress mediators and also protects against harmful compounds already formed after reacting with free radicals, such as lipid peroxides like MDA (malondialdehyde). Vitamin C – As a powerful antioxidant, vitamin C neutralizes free radicals that cause oxidative stress in the skin and lead to premature aging. It is also essential for collagen production in skin cells, which helps maintain skin structure and delay the signs of aging.

Because its anti-glycation action helps prevent the formation of new spots as well as combat existing ones.